NCBI Bookshelf. Newton 3. Wernicke-Korsakoff syndrome is a common complication of a thiamine deficiency that is primarily seen with alcoholics. However, less than a third of patients present with this complete triad. Wernicke encephalopathy is characterized by an acute confusional state with clinical features that are often reversible. While Korsakoff syndrome is characterized by confabulation, memory loss, and gait abnormalities that are often irreversible and results if Wernicke encephalopathy is not treated adequately.

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High consumption of alcohol, not only by the adult population but also, and ever increasing, by younger strata, presents itself as a worrisome public health issue.

One of the possible consequences of chronic alcohol consumption is the development of the Wernicke-Korsakoff syndrome. This disease, without proper treatment, can progress to a state of stupor, coma and even death.

The authors shed a light on its pathophysiology and manifestations and, in the process, a literary review was undertaken. Este enerva somente o recto lateral. The Wernicke Korsakoff syndrome and related disorders due to alcoholism and malnutrition. Clinical signs in the Wernicke-Korsakoff complex: a retrospective analysis of cases diagnosed at necropsy.

Kopelman md, Thomson ad, Guerrini i, marshall EJ. The Korsakoff syndrome: clinical aspects, psychology and treatment.

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Wernicke encephalopathy

Due to the close relationship between these two disorders, people with either are usually diagnosed with WKS as a single syndrome. It mainly causes vision changes, ataxia and impaired memory. The cause of the disorder is thiamine vitamin B 1 deficiency. This can occur due to beriberi , Wernicke encephalopathy, and alcoholic Korsakoff syndrome. These disorders may manifest together or separately. WKS is usually secondary to alcohol abuse. Wernicke encephalopathy and WKS are most commonly seen in people with an alcohol use disorder.


Wernicke–Korsakoff syndrome

Wernicke encephalopathy WE , also Wernicke's encephalopathy [1] is the presence of neurological symptoms caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in particular thiamine vitamin B1. The condition is part of a larger group of thiamine deficiency disorders, that includes beriberi in all its forms, and alcoholic Korsakoff syndrome. When it occurs simultaneously with alcoholic Korsakoff syndrome it is known as Wernicke—Korsakoff syndrome. Classically, Wernicke encephalopathy is characterised by the triad — ophthalmoplegia , ataxia , and confusion. The classic triad of symptoms found in Wernicke encephalopathy is: [7].


NCBI Bookshelf. Sarayu Vasan ; Anil Kumar. Authors Sarayu Vasan 1 ; Anil Kumar 2. Wernicke encephalopathy WE is an acute neurological condition characterized by a clinical triad of ophthalmoparesis with nystagmus, ataxia, and confusion. This is a life-threatening illness caused by thiamine deficiency, which primarily affects the peripheral and central nervous systems.


The Scientific Journal of the Spanish Society of Neurological Nursing publishes papers on topics of interest for nursing or health professionals in general, in any of their areas of activity, that help generate knowledge and are useful for the development of neurological nursing care. Preferably those that may have greater impact in clinical practice. The aim of Scientific Journal of the Spanish Society of Neurological Nursing is the research, study, dissemination and development of neurology at nursing level, as well as the development of neurological patient care, their family and environment. CiteScore measures average citations received per document published. Read more.

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